Unless
otherwise noted, the doses below are from Mader (1996)
and Frye (1993).
Note:
All drugs are administered s.i.d. unless otherwise indicated.
Antibiotics
Calcium
Parasites
Protozoans
Turtles
Miscellaneous
Antibiotics |
Dose |
Frequency |
Comments |
Amikacin
(amiglyde sulfate) |
5
mg/kg IM, then
2.5 mg/kg IM q 72 hr |
Highly
nephrotoxic - give with SC/IC fluids |
Amoxi
(amoxicillin) |
10
mg/kg IM q24h
22
mg/kg PO q 12-24 h
|
Ineffective
unless used with aminoglycosides (such as Amikacin) |
Baytril
(enrofloxacin) |
Lizards
and snakes:
Routine: 5 mg/kg IM/PO q 24h
Resistant: 10 mg/kg IM/PO q 24h
Tortoises:
7.5-10
mg/kg diluted with normal saline IM
|
All
reptiles: Highly cytotoxic and nephrotoxic - give
with SC/IC fluids. Injectible form may be administered
PO. NOTE: When given PO, it may
be mixed with a small amount of Syrpalta, banana,
applesauce, etc., to make it more palatable; increase
dose to 10 mg/kg for PO. There are now flavoring
agents vets can use to mix the orally administered
Baytil with making a more palatable medicine that
is easier and safer to administer than by injection.
Tortoises:
Give in front legs only, up to 21 days (Lancaster,
pers comm, 1997). May also give PO.
|
Flagyl
(metronidazole) |
150
mg/kg PO weekly |
anaerobes |
Fortaz
(ceftazidime) |
20
mg/kg SQ/IM q 72h * |
This is a 3rd generation cephalosporin
(newer than Baytril)used parenterally for gram-negative
infections, and is particularly, useful in reptiles.
May
cause pain on IM injection; SC injection probably
less painful. Is kept in freezer and must be brought
to room temperature before injecting.
May cause hypersensitivity reactions, diarrhea,
granulocytopenia, thrombocytopenia, mild azotemia.
May need to reduce dose in renal failure; use
with caution.
|
*
From Mader
From Plumb's Veterinary Drug Handbook, 5th Edition
Calcium |
Type |
Diagnosis |
Dose |
Comments |
Calcitonin
(Calcimar, Miacalcin) |
Hypercalcemia |
1.5
U/kg SC tid |
Need
additional fluids for diuresis. May be lethal if
given before Ca:P levels are normalized. |
Secondary
hyperparathyroidism |
50
U/kg IM once; rep in 2 wks if needed |
Calcium
glubionate (NeoCalglucon, Calci-Syrup, Sandoz |
Mild
MBD |
1
ml/kg PO bid |
OTC
in most states; can be ordered through pharmacies
if not otherwise in stock. |
Dystocia |
1
mg/kg PO bid up to 5 ml/d |
Continue
until eggs are laid; if not laid within 24 hrs,
consider needle aspiration or surgical extraction.
See Dystocia |
Calcium
gluconate (various manufacturers) |
Iguana:
hypocalcemia |
100
mg/kg IM qid prn |
. |
Calcium
lactate (Calphosan) |
hypocalcemia |
250
mg/ig IV, IM bid |
. |
Parasites |
Type |
Drug |
Dose
mg/kg |
Route |
Frequency |
Cestodes |
Tapeworm |
Praziquantel |
5-8
7.5
3.5-7
|
PO
PO
PO
|
rep
q 2 wks 1x
rep q 2 wks 1x for cestodes and trematodes in
some species
in
snakes
|
|
Niclosamide |
150 |
PO |
rep
q 2 wks 1x |
Nematodes |
Hepatic
worms |
Fenbendazole
(Panacur)* |
50-100 |
PO |
rep
q 2 wks 2-3x |
Hookworms |
Fenbendazole
(Panacur) |
50-100
25
|
PO
PO
|
rep
q 2 wks 2-3x
rep
q 2 wks until 4 negative fecals obtained
|
Lungworms |
Fenbendazole
(Panacur) |
50-100 |
PO |
rep
q 1wks 2-3x |
Pinworm
|
Sulfadimethoxine
(Albon) |
25 |
PO |
rep
q 6 days until negative fecals obtained |
Fenbendazole
(Panacur) |
100 |
PO |
rep
q 2 wks until negative fecals obtained |
Ivermectin
(Ivomec)* |
0.2 |
IM |
rep
q 2 wks 2-3x |
Piperacine
citrate |
50 |
PO |
rep
q 2 wks 2-3x |
Roundworm |
Fenbendazole
(Panacur) |
50-100 |
PO |
rep
in 2-3 wks |
100 |
PO |
rep
in 2 wks |
25 |
PO |
rep
q 2 d for 3 wks |
Strongyles |
Fenbendazole
(Panacur) |
50-100 |
PO |
rep
q 2 wks |
Thiabendazole |
25 |
PO |
rep
q 2 wks 2-3x |
Pyrantel
pamoate (Strongid-T) |
25 |
PO |
sid
2-4 d |
Pentastomids |
Fenbendazole
(Panacur) |
50-100
|
PO
|
rep
in 2 wks
|
Ivermectin
(Ivomec)* |
0.2
|
PO
|
rep
q 2 wks 2-3x
|
*
Ivermectin
is administered in near-toxic doses to be effective, and
must be repeated often 3 times to be as effective as the
far less toxic fenbendazole. Merck, the maker of ivermectin,
does not recommend its use in reptiles. Often fatal or
nearly so to small, debilitated reptiles. May cause paralysis,
blindness, etc. in larger reptiles. Its use is not recommended
for lizards and snakes; it is nearly always fatal when
used in turtles and tortoises. Ivermectin toxicity includes
paralysis and blindness.
From "Drug Dosage and Chemotherapeutics", by
Lara Maxwell, DVM, in Biology, Husbandry and Medicine
of the Green Iguana, E.R. Jacobson, DVM, ed.
From
VIN
From Plumb's Veterinary Drug Handbook, 5th edition
*Fenbendazole,
commonly sold under the brand name "Panacur",
is generally purchased by veterinary clinics in powdered
form. The powder is mixed with fluid as needed for oral
administration. Fenbendazole is also available in cream
form sold in tubes for horses. The calculations for fenbendazole
are as follows:
Cream |
kg
bodyweight x 0.25 = cc per dose
gm
bodyweight x 0.00025 = cc per dose
|
Compounded
liquid |
0.3-0.4
cc/lb. bodyweight per dose
0.66-0.88
cc/kg bodyweight per dose
|
Protozoans |
Type |
Drug |
Dose
mg/kg |
Route |
Frequency |
Amoebiasis |
Metronidazole
(Flagyl) |
24-50 |
PO |
rep
q 2 wks |
40 |
PO |
rep
q 2 wks |
125 |
PO |
rep
q 2 wks |
Coccidia |
Sulfadimethoxine |
50 |
PO |
q
3 d, rep in 3 d |
90
45 |
PO/IM |
first
day, then
q d x 5 d |
Sulfadiazine |
75
45 |
PO |
first
day, then
q d x 5 d |
Flagellates |
Metronidazole
(Flagyl) |
25-50 |
PO |
rep
in 3-4 d PRN |
Dosages
Specific To Turtles
Franklin Gould, Journal
of Wildlife Rehabilitation, 1998 |
Condition |
Drug |
Dosage |
Comments |
Parasites |
Amoebiasis,
Trichomoniasis |
Metronidazole |
50
mg/kg PO; rep 2 wks |
. |
Coccidia |
Sulfadimethoxine |
30
mg/kg PO d for 10 d |
. |
Tapeworms |
Praziquantel |
5-8
mg/kg PO; rep in 2 wks |
. |
Roundworms,
Hookworms, Lungworms, Heartworms |
Fenbendazole |
40-50
mg/kg PO; rep 2 wks, 2-3 x |
. |
Antibiotics
Note: Never use piperazine or ivermectin
on any turtle. Both have been demonstrated to
have toxic, if not lethal, effects on turtles.
Per Melissa Kaplan: these are also the drugs
and dosages generally used for other reptiles
|
Amikacin |
2.5
mg/kg every 72 hrs IM |
up
to 5 mg/kg for 48 hr with fluid support |
Amoxicillin |
10
mg/kg per d for 7 d SQ |
w/aminoglycosides |
Ampicillin |
10
mg/kg per d for 7 d SQ |
up
to 20 mg/kg q d |
Baytril
(enrofloxacin) |
5
mg/kg per d for 10 d SQ
|
up
to 10 mg/kg q d
up
to 15 mg/kg for 72 hr in tortoises with URI
After
the initial injection by vet, the injectible may
be given by mouth, increasing dose to 10 mg/kg
per d for 10 day [K. Harkewicz VMD 2002]
|
Ceftriaxone |
50
mg/kg per d for 7 d SQ |
. |
Chloramphenical |
50
mg/kg per d for 7 d SQ |
. |
Gentamicin |
2.5
mg/kg every 72 hours IM |
up
to 10 mg/kg for 48 hr w/fluid support |
Tetracycline |
50
mg/kg per d for 7 d SQ |
. |
Trimethoprim-Sulfa |
30
mg/kg per d for 7 d PO |
. |
Tylocin |
5
mg/kg per d for 7 d SQ |
. |
Anti-Viral |
Acyclovir
(Zovirax 5%) |
Topical,
applied daily |
. |
Supplements |
Vit
A injectable |
It
is recommended that this be givin in doses of less
than 2000 IU per injection due to potential toxicity |
Cod
Liver Oil |
1-2
drops twice per week added to food |
. |
Miscellaneous
Drugs, Dosages |
Type |
Dose |
Comment |
Other |
Lactated
ringers |
Tortoises:
15-25 ml/kg q 24 hr SQ part vic
Reptiles:
15-20 ml/kg q 24 hrs part vic
|
. |
Lancaster,
pers comm, 1997
Barten,
pers comm, 1995
|
Slurries |
Nutri-Cal:
1-2 ml/kg q 24 hr part vic
Food*:
2% bodyweight q 24-48 hr part vic
|
Reptile
stomach capacity: 25-100 ml/kg |
Barten,
pers comm, 1995 |
*For
slurry recipes, see Emaciation
(Starvation) Protocol
Glossary
of Drug-Related Terms
Deciphering
Prescriptions
|